What Is the HCG Diet, and How Does the Fad Diet Work?

The diet requires that you eat only 500 calories a day, supposedly as part of an effort to help reset your metabolism and change your abnormal eating patterns, as the FDA explains in its warning against the diet. (1) The HCG diet also requires you to take a daily dose of the hormone human chorionic gonadotropin (HCG). Available in injections, pellets, sprays, oral drops, and pills, HCG is the hormone produced by the placenta during pregnancy.

In 1954, British physician A.T.W. Simeons theorized that HCG allows mothers-to-be to access fat reserves to feed their fetuses. He published a book, Pounds and Inches: A New Approach to Obesity, in which he suggested that HCG could help people access their fat reserves and achieve weight loss.

The idea might have been that, if a woman had morning sickness or some other condition that prevented her from taking in ample nutrition at a certain point in her pregnancy, her baby would still have a reserve of energy to draw on, and the hormone HCG could help facilitate access to that supply, Weinandy says. But, she notes, this really oversimplifies the numerous systems at work in pregnancy: A number of hormones are active, and the way they interact can sometimes even promote fat gain for the mother.

In fact, Weinandy says, this kind of speculation about HCG’s role in weight loss can be “really dangerous, and it’s sending a bad message to people because we don’t know for certain how HCG works.” Another worry? Many chronic diseases, including breast cancer and prostate cancer, have been linked to an imbalance of hormones, so we can’t predict what effects manipulating our hormones might have, Weinandy cautions.

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HCG is a hormone that is naturally produced by the female placenta during a normal pregnancy. This medicine’s action is highly similar to luteinizing hormone (LH). If it is combined with other medicines and drugs, HCG Pregnyl is highly effective in helping female patients become pregnant.

HCG Pregnyl is a popular medicine that is regularly prescribed to female patients as part of a regimen that is supposed to induce:

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Ovulation induction in subfertility that is usually triggered by impaired follicle-ripening or by anovulation. – Luteal phase support.

Follicle preparation for puncture in controlled ovarian hyperstimulation programs (this usually occurs in the case of medically assisted reproductive methods and techniques).

HCG Pregnyl is a medicine that is regularly prescribed to male patients because of its ability to induce

Hypogonadotrophic hypogonadism – Some patients who were suffering from idiopathic dysspermias have positively responded to a treatment with this medicine– Cryptorchidism, (not the one that is triggered by an abnormal anatomical obstruction).

Warnings

In the case of female patients who want to be treated with HCG Pregnyl:

Since infertile female patients who undergo medically assisted reproduction (especially those who need in vitro fertilization), are known to often be suffering from tubal abnormalities, after a treatment with this drug they might experience much more ectopic pregnancies. This is why early ultrasound confirmation at the beginning of a pregnancy (to see whether the pregnancy is intrauterine or not) is crucial.

In the case of male patients: A prolonged treatment with HCG Pregnyl is known to regularly lead to increased production of androgen. Therefore:

Patients who are suffering from overt or latent cardiac failure, hypertension, renal dysfunction, migraine or Epilepsy might not be allowed to start using this medicine or might have to be prescribed a lower dose of HCG Pregnyl.

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Dosage

Dosage in the case of female patients: They should be administered one injection of 5 000-10 000 I.U. of this medicine. Dosage in the case of male patients: They should be administered an injection of 1000-2000 I.U. of medicine, from 2 to 3 times each week. It is best that each dose of HCG Pregnyl should be administered by an authorized medical healthcare provider.

Side effects

A prolonged treatment with this medicine is known to trigger several reactions at the injection site (like pain, bruising, redness, itching and swelling).

Female patients who have been treated with this product have experienced unpleasant ovarian hyperstimulation syndrome. especially after the patient has been administered a high dose of this medicine (this condition is probably triggered by an excessive androgen production). In some cases, a treatment with HCG Pregnyl may sometimes cause gynaecomastia.

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